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id="qc8kq4cmsca4" class="art-info"> 發(fā)布時間： 2021-04-27　　點擊次數(shù)： 1047次 </div> <div id="qc8kq4cmsca4" class="art-body"> <div>　　小動物麻醉機(jī)淺析常用實驗動物的麻醉與鎮(zhèn)痛</div><div>　　麻醉（Anesthesia）是指用物理或化學(xué)藥品的方法，暫時性抑制動物體全身或局部的痛覺或痛覺傳導(dǎo)，使痛覺消失或痛覺遲鈍，以便順利進(jìn)行手術(shù)叫做麻醉。實驗動物的麻醉方法有全身麻醉和局部麻醉兩種。</div><div>　　1. 全身麻醉</div><div>　　1.1 吸入性全身麻醉</div><div>　　吸入性麻醉是將揮發(fā)性液體麻醉藥或氣體麻醉藥經(jīng)呼吸道吸入體內(nèi)，從而產(chǎn)生麻醉作用的方法。常見的藥物有安氟醚、異氟醚、氧化亞氮等。吸入性麻醉藥的特點是安全范圍大，肌肉能*松弛，對肝和腎的毒性較小，麻醉的誘導(dǎo)期和蘇醒期較短，麻醉深度易于掌握，而且麻醉后恢復(fù)比較快。吸入性麻醉劑必須使用帶有揮發(fā)罐的麻醉機(jī)對動物進(jìn)行麻醉。</div><div>　　1.2 非吸入性全身麻醉</div><div>　　非吸入麻醉是將某種全身麻醉藥通過皮下、肌肉、靜脈或腹腔等途徑注入動物體內(nèi)而產(chǎn)生麻醉作用的方法。其特點是操作簡便，不需要特殊的麻醉裝置，一次給藥可維持較長時間，麻醉過程較平穩(wěn)，動物無掙扎現(xiàn)象，因此是目前臨床上常用的麻醉方法。缺點是蘇醒較慢，麻醉深度和使用劑量較難掌握。常用藥物包括戊巴比妥鈉、烏拉坦、*等。</div><div>　　2. 局部麻醉</div><div>　　局部麻醉是利用某些藥物有選擇性地暫時阻斷神經(jīng)末梢、神經(jīng)纖維以及神經(jīng)干的沖動傳導(dǎo)，從而使其分布或支配的相應(yīng)局部組織暫時喪失痛覺。其特點是動物保持清醒，對重要器官功能干擾輕微，麻醉并發(fā)癥少，是一種比較安全的麻醉方法。適用于大中型動物各種短時間內(nèi)的實驗。常用的局部麻醉藥有鹽酸普魯卡因、鹽酸利多卡因和鹽酸丁卡因。</div> </div> <div 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